Contemporary research in behavioral pharmacology
نویسندگان
چکیده
منابع مشابه
Perspectives in Pharmacology Combinatorial Chemistry and Contemporary Pharmacology
Both solidand liquid-phase combinatorial chemistry have emerged as powerful tools for identifying pharmacologically active compounds and optimizing the biological activity of a lead compound. Complementary high-throughput in vitro assays are essential for compound evaluation. Cell-based assays that use optical endpoints permit investigation of a wide variety of functional properties of these co...
متن کاملCombinatorial chemistry and contemporary pharmacology.
Both solid- and liquid-phase combinatorial chemistry have emerged as powerful tools for identifying pharmacologically active compounds and optimizing the biological activity of a lead compound. Complementary high-throughput in vitro assays are essential for compound evaluation. Cell-based assays that use optical endpoints permit investigation of a wide variety of functional properties of these ...
متن کاملBehavioral pharmacology of pain.
Behavioral methods are extensively used in pain research. Rodent modeling tends to rely on evoked responses but there is a growing interest in behavioral readouts that may capture elements of ongoing pain and disability, reflecting the major clinical signs and symptoms. Clinically, analgesics show greater efficacy in acute pain after standard surgery than in chronic conditions but are never com...
متن کاملThe behavioral pharmacology of hallucinogens.
Until very recently, comparatively few scientists were studying hallucinogenic drugs. Nevertheless, selective antagonists are available for relevant serotonergic receptors, the majority of which have now been cloned, allowing for reasonably thorough pharmacological investigation. Animal models sensitive to the behavioral effects of the hallucinogens have been established and exploited. Sophisti...
متن کاملBehavioral Pharmacology: The Current Status
more extensive references. These points do not detract from the utility and comprehensibility of this chapter. The novelty of utilizing NMR in biologic systems precludes its presentation in an applied manner. The author of this section appropriately provides a rigorous, though understandable, account of the theory and physics behind this technique. In a logical sequence the reader is introduced...
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ژورنال
عنوان ژورنال: Drug Development Research
سال: 1990
ISSN: 0272-4391,1098-2299
DOI: 10.1002/ddr.430200102